REXEED Dialyzers by Asahi

REXEED Dialyzers

Asahi has achieved a new level of overall performance in dialyzer design by combining the new polysulfone membrane REXBRANE with a new jacket design allowing for optimum flow dynamics. Incorporated on the inner surface is Asahi's unique hydrophilic gel layer technology. This minimizes blood membrane interaction and plays a crucial role in anticoagulation requirements. All has come together to create the new REXEED S (single use) and REXEED R (multiple-use) dialyzer.

A New Level of Overall Performance

Highest performance dialyzer in the US
Improved anticoagulation / less heparin
Available in four sizes:
2.5m2 / 2.1m2 / 1.8m2 / 1.5m2
2.5 m2 - highest performance dialyzer offered today
1.5 m2 is ideal for Acute Patients
Single and Multiple use
Gamma sterilized (No ETO residuals )
2.5m2 - Alternative to “Tandem Dialysis”
High middle molecule removal
Next generation polysulfone membrane REXBRANE
Exceptional urea, creatinine and phosphate clearances

Improved Anticoagulation
Asahi’s unique membrane technology contributes to improved anticoagulation. Asahi’s hydrophilic gel layer helps to reduce the interaction between blood components and the membrane surface as illustrated below.

REXEED Dialyzers Improved Anticoagulation Hydrophilic Gel Layer

This reduces the potential for platelet activation and protein adhesion to the membrane. REXEED dialyzers frequently require less heparin than other dialyzers (graph below).

REXEED and Heparin usage

Improved Flow Dynamics
The improved flow dynamics of REXEED are provided by Asahi’s new high performance jacket design that provides a uniform dialysate flow.
The waved fiber design in REXEED provides smooth blood flow and improved dailysate penetration into the middle of the bundle for ideal dialysate / fiber contact and ideal small molecule clearance.

REXEED Dialyzer Improved Flow Dynamics

The ideal flow pattern is shown as a symmetrical sharp peak (above) that suggests quick dialysate turnover leading to exceptional small molecule clearance.

Balanced and Comprehensive
Small Molecule Clearance
REXEED has been developed to provide well balanced and comprehensive small and middle molecule clearance while minimizing albumin loss. This is demonstrated by the triangular graph (below).

REXEED Dialyzers

REXEED Dialyzer Specifications

Dialyzer	Size M2	Flux	Sterilization	Use	Membrane	KOA	Package
REXEED 15	1.5	Hi-Flux	Gamma	Single / Re-Use	Polysulfone (Rexbrane)	1232	12 / Case
REXEED 18	1.8	Hi-Flux	Gamma	Single / Re-Use	Polysulfone (Rexbrane)	1483	12 / Case
REXEED 21	2.1	Hi-Flux	Gamma	Single / Re-Use	Polysulfone (Rexbrane)	1683	12 / Case
REXEED 25	2.5	Hi-Flux	Gamma	Single / Re-Use	Polysulfone (Rexbrane)	1881	12 / Case

REXEED Dialyzer Performance (in vitro)

	REXEED-15				REXEED-18
	Qd=500ml/min			Qd=800 ml/min	Qd=500ml/min			Qd=800 ml/min
Clearance mL/min	Qb=200 mL/min	Qb=300 mL/min	Qb=400 mL/min	Qb=400 mL/min	Qb=200 mL/min	Qb=300 mL/min	Qb=400 mL/min	Qb=400 mL/min
Urea	196	272	317	352	198	280	330	366
Creatinine	191	255	296	326	194	265	309	341
Phosphate	185	238	272	301	190	250	289	320
Vitamin B12	142	168	179	199	152	183	197	219
KOA (Urea)	1232				1483
UFR (mL/hr/mmHG)	63				71

	REXEED-21				REXEED-25
	Qd=500ml/min			Qd=800 ml/min	Qd=500ml/min			Qd=800 ml/min
Clearance mL/min	Qb=200 mL/min	Qb=300 mL/min	Qb=400 mL/min	Qb=400 mL/min	Qb=200 mL/min	Qb=300 mL/min	Qb=400 mL/min	Qb=400 mL/min
Urea	199	284	340	374	199	287	350	380
Creatinine	195	272	317	352	196	280	330	364
Phosphate	192	257	299	334	194	260	303	346
Vitamin B12	160	194	212	236	163	199	225	251
KOA (Urea)	1683				1881
UFR (mL/hr/mmHG)	74				80